Epinephrine
Epinephrine: Most reliable way to restart a heart: 15 mL gives 99% resuscitation. Also used for the adrenaline effect. In-game item, not medical advice.
Use, trade-offs and mechanics
Epinephrine supplies a timed adrenaline effect and repeated opportunities to restart a stopped heart. A combat pen's fifteen milliliters corresponds to ninety seconds in the community model. During that effect the game sets adrenaline to one hundred and rolls a five-percent restart chance each second, provided the brain is still alive.
The often quoted ninety-nine-percent figure is a modeled chance across that ninety-second duration, not a promise that every pen works instantly. More time means more rolls, but a character in cardiac arrest may lose consciousness and brain integrity before enjoying the whole duration. The presence of an auto-pump also changes how much time is practically available.
Route matters. Drinking one hundred milliliters supplies one hundred seconds, whereas injected liquid gives six seconds per milliliter. Increasing the effect beyond two hundred forty seconds forces fibrillation in the reference. The commonly stated forty-milliliter injection boundary follows from that duration rule; it is not a reason to keep injecting until that amount is reached.
A successful restart leaves fibrillation at fifty instead of clearing it completely. Continued rhythm management therefore remains relevant after the pulse returns. A defibrillator's successful shock has a different outcome, clearing fibrillation, but each shock has a much lower recorded restart chance. Epinephrine also reduces the perception of pain through adrenaline; it does not repair the underlying injured tissue or remove the cause of arrest.
Documented properties
| Property | Documented value | Status |
|---|---|---|
| type | Fluid | 1 community source |
| category | cardiac | 1 community source |
| effect | Sets adrenaline to 100 each second; 5% chance per second to restart a stopped heart | 1 community source |
| dosage | Combat pen 15 mL = 90 s; 1 mL = 6 s | 1 community source |
| risk | Above 40 mL injected forces fibrillation | 1 community source |
| treats | Cardiac arrest | 1 community source |
| obtain | Mini-barrel, combat pen | 1 community source |
| craftable | No | 1 community source |


Questions
Where does this Epinephrine information come from?
1 source · community wiki; store and publisher establish game context only. See the dated Sources table for the exact pages.
Related guides
Sources
| Source | Checked |
|---|---|
| Miraheze — Epinephrine (liquid) | 2026-11-12 |
| Miraheze — Heart | 2026-11-12 |