Brain Damage
Brain Damage: Track brain integrity in the health panel; below 95% periodic effects begin.
Use, trade-offs and mechanics
Brain integrity is the game's final survival boundary: it begins at one hundred, and reaching zero ends the run. It is different from a temporary consciousness loss. A character can be unconscious while alive, but the community reference does not allow ordinary recovery after brain integrity reaches zero.
Head impacts and low blood oxygen are important causes. Below eighty SpO2, the reference applies continuing brain damage according to the oxygen deficit. Failed shrapnel removal from the head can also damage the brain. Removing the cause is therefore part of recovery: taking a brain-restoring item while severe hypoxia continues leaves two competing processes active.
Four moodle thresholds describe worsening integrity: below ninety-five, eighty, sixty and thirty. The thirty threshold also matters because consciousness cannot exceed current brain health; below it the character becomes comatose. Speech can become slurred before that, and low integrity can cause item drops, control reversal, hallucinated attacks and other periodic effects. A bite-like sound without a new bleeding injury may be a hallucination, not proof of another enemy hit.
Natural recovery is very slow. Braingrow supplies gradual recovery with RNRS restrictions, the first neural booster provides an instant increase, and mindwipe is a much larger trade-off with permanent run consequences. Those are different treatments rather than interchangeable health potions. Compare current oxygen, integrity and RNRS before selecting one. The current community Brain page is the source for these numerical mechanics; several linked wiki articles do not constitute independent confirmation.
Documented properties
| Property | Documented value | Status |
|---|---|---|
| cause | Head impact, low blood oxygen (SpO2 below 80), failed shrapnel removal from the head | 1 community source |
| symptoms | Brain damage moodles 1–4; six periodic effects including attack hallucinations, speech loss, consciousness loss | 1 community source |
| progression | Starts at 100; death at 0; self-heals 0.003%/s; loses (80−SpO2)/600 per second below 80 | 1 community source |
| treatment | Braingrow (+10 over 100 s), neural booster (+10 first use), mindwipe (+50, capped at 96) | 1 community source |
| complications | Fibrillation, stroke, coma, death | 1 community source |
| prevention | Treat hypoxia and head trauma early; avoid unnecessary head shrapnel removal | 1 community source |


Questions
Where does this Brain Damage information come from?
1 source · community wiki; store and publisher establish game context only. See the dated Sources table for the exact pages.
Related guides
Sources
| Source | Checked |
|---|---|
| Miraheze — Brain | 2026-11-12 |
| Miraheze — Moodles | 2026-11-12 |